Fibroma of the ovary associated with ascites and hydrothorax was reported by cullingworth in 1879, demons in 1887, and tait in 1892 1, 2. Pdf meigs syndrome represents a triad of pleural effusion, ascites, and an ovarian tumor. Nonclassic meigs syndrome and demons meigs syndrome. The more frequently observed type of ovarian tumor is the fibroma. Socalled meigs syndrome associated with benign and. Pseudo meigs syndrome is characterised by pleural effusion, ascites and benign ovarian tumours other than fibromas as described by meigs. Meigs syndrome is defined as the presence of a benign ovarian tumor with pleural effusion and ascites that. The term nonclassic meigs syndrome was applied for patients with ascites and pleural effusion associated with benign ovarian, fallopian tube, or broad ligament tumors other than those included in the definition of classic meigs syndrome table table1. Find, read and cite all the research you need on researchgate. A case of meigs syndrome with preceding pericardial. Meige syndrome genetic and rare diseases information. This clinical syndrome was definitely established in 1937, when meigs and cass reported a series of 7 cases of ovarian fibroma with ascites and hydrothorax.
In the vast majority 8090% of cases, the primary tumor is an ovarian fibroma. She initially presented to her personal physician in july, 2003, with a 2month history of progressive dyspnoea, abdominal distension, and pedal oedema. It is a rare clinical entity, which is also considered to be an uncommon complication of benign leiomyomas of the female genital tract. The authors present a case of meigs syndrome with an ovarian fibroma. Meigs syndrome is defined as the presence of ascites and pleural effusion in association with a benign, usually solid ovarian tumor. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree. Meigs separated his definition into true meigs syndrome, which he preferred to call demons meigs syndrome and pseudo meigs syndrome distinguished by different tumor. The case of a 33 yearold female patient who presented rapid weight loss and a quickly increasing abdominal circumference is. Meigs syndrome in a young woman with a normal serum ca125. Meigssyndrome this condition disappears after removal of the pelvic tumor. Thus in view of the frequency of ovariantumours the syndrome is rare.
Physical examination showed dullness in thoracic percussion bilaterally and abdominal distension. The tumours may include those of the fallopian tube, uterus, round ligament, mature teratomas, struma ovarii or ovarian leiomyomas, as well as those originating in the colon, breast and stomach 4. Pleural effusion in meigs syndrometransudate or exudate. In 1937, meigs described a syndrome of ovarian fibromas with ascites and hydrothorax that quickly resolved on removal of the fibroma. In september, 2003, a 33yearold woman was referred to our medical facility. Medical care of patient with meigs syndrome involves paracentesis and thoracentesis for ascites and pleural effusion respectively. The criteria for the diagnosis of meigss syndrome are the simultaneous appearance of. Because the transdiaphragmatic lymphatic channels are larger in diameter on the right, the pleural.
Meigs syndrome should be included in the differen tial diagnosis of young women presenting with pleural effusion. Meigs syndrome resolves after the resection of the tumor. Ovarian fibroma with meigs syndrome associated with. Meigs syndrome is a strange clinical entity that is also considered to be an uncommon complication of fibroma of the female genital tract. The benign tumors in meigs syndrome are usually fibromas or fibrothecomas and constitute 4% of all ovarian neoplasms. For language access assistance, contact the ncats public information officer. According to some authors, these cases, together with the cases meeting. Meigs syndrome is the association of ovarian fibroma, pleural effusion, and ascites that may also cause marked elevation of ca125.
Ca 125, cavity effusions, ovarian cancer, pseudomeigs syndrome. We present a case of meigs syndrome due to right ovarian fibroma with. If you have problems viewing pdf files, download the latest version of adobe reader. They focus on the evaluation of pleural fluid in the setting of an ovarian mass and then briefly discuss the imaging of ovarian fibromas and. Treatment is as for the accompanying pericardial effusion chapter 77. Ovarian fibroma represents 2 to 5% of ovarian tumor and out of this only 1 to 2% of cases present as meigs syndrome.
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